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Regeneration Tensed Up: Polyploidy Takes the Lead.

Authors :
Spiró Z
Heisenberg CP
Source :
Developmental cell [Dev Cell] 2017 Sep 25; Vol. 42 (6), pp. 559-560.
Publication Year :
2017

Abstract

The cellular mechanisms allowing tissues to efficiently regenerate are not fully understood. In this issue of Developmental Cell, Cao et al. (2017) discover that during zebrafish heart regeneration, epicardial cells at the leading edge of regenerating tissue undergo endoreplication, possibly due to increased tissue tension, thereby boosting their regenerative capacity.<br /> (Copyright © 2017. Published by Elsevier Inc.)

Details

Language :
English
ISSN :
1878-1551
Volume :
42
Issue :
6
Database :
MEDLINE
Journal :
Developmental cell
Publication Type :
Academic Journal
Accession number :
28950096
Full Text :
https://doi.org/10.1016/j.devcel.2017.09.008