Radiation-Induced Malignancies Making Radiotherapy a "Two-Edged Sword": A Review of Literature.

Radiotherapy is one of the modalities of treatment of malignancies. Radiation-induced malignancies (RIMs) are late complications of radiotherapy, seen among the survivors of both adult and pediatric cancers. Mutagenesis of normal tissues is the basis for RIMs. The aim of this review of literature was to discuss epidemiology, factors affecting and different settings in which RIM occur.
Competing Interests: All authors declare that they have no conflicts of interest.