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Molecular and clinical heterogeneity of adult diffuse low-grade IDH wild-type gliomas: assessment of TERT promoter mutation and chromosome 7 and 10 copy number status allows superior prognostic stratification.
- Source :
-
Acta neuropathologica [Acta Neuropathol] 2017 Dec; Vol. 134 (6), pp. 957-959. Date of Electronic Publication: 2017 Oct 19. - Publication Year :
- 2017
- Subjects :
- Adult
Aged
Brain Neoplasms pathology
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 7
DNA Copy Number Variations
Female
Follow-Up Studies
Glioma pathology
Humans
Isocitrate Dehydrogenase genetics
Male
Middle Aged
Mutation
Neoplasm Grading
Prognosis
Promoter Regions, Genetic
Survival Analysis
Telomerase genetics
Young Adult
Brain Neoplasms genetics
Brain Neoplasms metabolism
Glioma genetics
Glioma metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1432-0533
- Volume :
- 134
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Acta neuropathologica
- Publication Type :
- Editorial & Opinion
- Accession number :
- 29052002
- Full Text :
- https://doi.org/10.1007/s00401-017-1781-z