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Functionalized electromagnetic actuation method for aggregated nanoparticles steering.
- Source :
-
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference [Annu Int Conf IEEE Eng Med Biol Soc] 2017 Jul; Vol. 2017, pp. 885-888. - Publication Year :
- 2017
-
Abstract
- Despite the promising results in magnetic nanoparticles (MNPs) based targeted drug delivery (TDD), the aggregation of the magnetic nanoparticles deteriorates targeting performance. This paper aims to introduce a magnetic actuation function for aggregated nanoparticles steering in vascular network. To improve the drug delivery performance, first the governing dynamics has been introduced, next the modified field function (MFF) concept has been proposed and finally a computational platform for a Y-shape channel has been used to simulate the particles steering performance. The results showed an acceptable agreement with the experimental results. The proposed actuation method enables us to more accurately steer aggregated nanoparticles and improves targeting performance.
- Subjects :
- Drug Delivery Systems
Electromagnetic Phenomena
Magnetics
Magnetite Nanoparticles
Subjects
Details
- Language :
- English
- ISSN :
- 2694-0604
- Volume :
- 2017
- Database :
- MEDLINE
- Journal :
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
- Publication Type :
- Academic Journal
- Accession number :
- 29060014
- Full Text :
- https://doi.org/10.1109/EMBC.2017.8036966