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Directed Evolution: Bringing New Chemistry to Life.

Authors :
Arnold FH
Source :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2018 Apr 09; Vol. 57 (16), pp. 4143-4148. Date of Electronic Publication: 2017 Nov 28.
Publication Year :
2018

Abstract

Tailor-made: Discussed herein is the ability to adapt biology's mechanisms for innovation and optimization to solving problems in chemistry and engineering. The evolution of nature's enzymes can lead to the discovery of new reactivity, transformations not known in biology, and reactivity inaccessible by small-molecule catalysts.<br /> (© 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.)

Subjects

Subjects :
Biocatalysis
Boranes chemistry
Cytochromes c chemistry
High-Throughput Screening Assays
Rhodothermus enzymology
Silanes chemistry
Boranes metabolism
Cytochromes c metabolism
Directed Molecular Evolution
Protein Engineering
Silanes metabolism

Details

Language :
English
ISSN :
1521-3773
Volume :
57
Issue :
16
Database :
MEDLINE
Journal :
Angewandte Chemie (International ed. in English)
Publication Type :
Academic Journal
Accession number :
29064156
Full Text :
https://doi.org/10.1002/anie.201708408
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