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Outcomes of surgical intervention for anomalous aortic origin of a coronary artery: A large contemporary prospective cohort study.
- Source :
-
The Journal of thoracic and cardiovascular surgery [J Thorac Cardiovasc Surg] 2018 Jan; Vol. 155 (1), pp. 305-319.e4. Date of Electronic Publication: 2017 Sep 14. - Publication Year :
- 2018
-
Abstract
- Objective: The purpose of this study was to prospectively analyze the outcomes of patients with anomalous aortic origin of a coronary artery undergoing surgical intervention according to a standardized management algorithm.<br />Methods: All patients aged 2 to 18 years undergoing surgical intervention for anomalous aortic origin of a coronary artery between December 2012 and April 2017 were prospectively included. Patients underwent stress nuclear perfusion imaging, stress cardiac magnetic resonance imaging, and retrospectively electrocardiogram-gated computed tomography angiography preoperatively. Patients were cleared for exercise at 3 months postoperatively if asymptomatic and repeat stress nuclear perfusion imaging, stress cardiac magnetic resonance imaging, and computed tomography angiography showed normal results.<br />Results: A total of 44 patients, with a median age of 14 years (8-18 years), underwent surgical intervention: 9 (20%) for the anomalous left coronary artery and 35 (80%) for the anomalous right coronary artery. Surgical procedures included unroofing in 35 patients (80%), translocation in 7 patients (16%), ostioplasty in 1 patient (2%), and side-side-anastomosis in 1 patient (2%). One patient who presented with aborted sudden cardiac death from an anomalous left coronary and underwent unroofing presented 1 year later with a recurrent episode and was found to have an unrecognized myocardial bridge and persistent compression of the coronary requiring reintervention. At last follow-up, 40 patients (91%) are asymptomatic and 4 patients have nonspecific chest pain; 42 patients (95%) have returned to full activity, and 2 patients are awaiting clearance.<br />Conclusions: Surgical treatment for anomalous aortic origin of a coronary artery is safe and should aim to associate the coronary ostium with the correct sinus, away from the intercoronary pillar. After surgery, the majority of patients are cleared for exercise and remain asymptomatic. Longer follow-up is needed to assess the true efficacy of surgery in the prevention of sudden cardiac death.<br /> (Copyright © 2017 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Adolescent
Child
Computed Tomography Angiography methods
Female
Humans
Magnetic Resonance Imaging, Cine methods
Male
Myocardial Perfusion Imaging methods
Outcome and Process Assessment, Health Care
Replantation methods
United States
Aorta abnormalities
Aorta diagnostic imaging
Aorta surgery
Chest Pain diagnosis
Chest Pain etiology
Chest Pain physiopathology
Coronary Vessel Anomalies diagnosis
Coronary Vessel Anomalies physiopathology
Coronary Vessel Anomalies surgery
Coronary Vessels diagnostic imaging
Coronary Vessels surgery
Postoperative Complications diagnosis
Postoperative Complications physiopathology
Vascular Surgical Procedures adverse effects
Vascular Surgical Procedures methods
Subjects
Details
- Language :
- English
- ISSN :
- 1097-685X
- Volume :
- 155
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Journal of thoracic and cardiovascular surgery
- Publication Type :
- Academic Journal
- Accession number :
- 29074047
- Full Text :
- https://doi.org/10.1016/j.jtcvs.2017.08.116