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Isolation of bastadin-6-O-sulfate and expedient purifications of bastadins-4, -5 and -6 from extracts of Ianthella basta.

Authors :
Gartshore CJ
Salib MN
Renshaw AA
Molinski TF
Source :
Fitoterapia [Fitoterapia] 2018 Apr; Vol. 126, pp. 16-21. Date of Electronic Publication: 2017 Dec 05.
Publication Year :
2018

Abstract

Bastadin-6-34-O-sulfate ester (8) was isolated from methanol extracts of Ianthella basta. The structure of 8 was characterized by analysis of MS and NMR data, and conversion through acid hydrolysis, to the parent compound, bastadin-6, which was identical by HPLC, MS and NMR with an authentic sample. An improved procedure for procurement of pure samples of bastadins-4 (4), -5 (5) and -6 (6) is described.<br /> (Copyright © 2017 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1873-6971
Volume :
126
Database :
MEDLINE
Journal :
Fitoterapia
Publication Type :
Academic Journal
Accession number :
29221701
Full Text :
https://doi.org/10.1016/j.fitote.2017.12.003