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Two Years Follow-Up of Patients with Abnormal Uterine Bleeding after Insertion of the Levonorgestrel-Releasing Intrauterine System.
- Source :
-
Gynecologic and obstetric investigation [Gynecol Obstet Invest] 2018; Vol. 83 (6), pp. 569-575. Date of Electronic Publication: 2017 Dec 08. - Publication Year :
- 2018
-
Abstract
- Aim: To evaluate the efficacy and safety of levonorgestrel-releasing intrauterine system (LNG-IUS) in the long-term treatment of heavy menstrual blood loss in women unrelated to intrauterine pathology.<br />Methods: One hundred and six parous women aged 33-48 years with recurrent heavy menstrual bleeding (HMB) participated in this study. The women were followed up for 24 months and were assessed for intensity of bleeding both for pre- and post-insertion periods. An LNG-IUS was inserted in each patient within 7 days of the start of menstrual flow. The women were followed up at 1, 3, 6, 12, 18, and 24 months following the insertion of the intrauterine device.<br />Results: One hundred and two women completed the follow-up period and had a significant reduction in the amount of menstrual blood loss. The LNG-IUS was well tolerated by all women. Pre-treatment of the use of the LNG-IUS, endometrial biopsy patterns for irregular proliferative endometrium and for atypical simple hyperplasia were 34/106 (32.08%) and 61/106 (57.55%) respectively and after treatment no abnormal pathologic findings were determined (p < 0.001).<br />Conclusion: Our findings indicate that the LNG-IUS is effective for significantly reducing the amount of menstrual blood loss in women with HMB.<br /> (© 2017 S. Karger AG, Basel.)
- Subjects :
- Adult
Contraceptive Agents, Female adverse effects
Female
Follow-Up Studies
Humans
Levonorgestrel adverse effects
Menstruation drug effects
Middle Aged
Prospective Studies
Treatment Outcome
Turkey
Contraceptive Agents, Female administration & dosage
Endometrium pathology
Intrauterine Devices, Medicated adverse effects
Levonorgestrel administration & dosage
Menorrhagia therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1423-002X
- Volume :
- 83
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Gynecologic and obstetric investigation
- Publication Type :
- Academic Journal
- Accession number :
- 29223999
- Full Text :
- https://doi.org/10.1159/000480012