Synthesis of carbohydrate conjugated 6A,6D-bifunctionalized β cyclodextrin derivatives as potential liver cancer drug carriers.

Authors :: Ding Y
Vara Prasad CVNS
Ding C
Wang B
Source :: Carbohydrate polymers [Carbohydr Polym] 2018 Feb 01; Vol. 181, pp. 957-963. Date of Electronic Publication: 2017 Nov 20.
Publication Year :: 2018
Abstract: Galactosyl and lactosyl conjugated 6A,6D-bifunctionlized β cyclodextrin derivatives were designed and synthesized as the potential liver cancer drug carriers through SN2 replacement and click reactions in order to increase liver cancer drug's targeting ability, solubility and stability. The synthetic methods and strategies to obtain the designed compounds were discussed.<br /> (Copyright © 2017 Elsevier Ltd. All rights reserved.)

Subjects :: Antineoplastic Agents therapeutic use
Carbohydrates chemistry
Drug Carriers chemistry
Indicators and Reagents
beta-Cyclodextrins chemistry
Carbohydrates chemical synthesis
Drug Carriers chemical synthesis
Liver Neoplasms drug therapy
beta-Cyclodextrins chemical synthesis

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