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Mechanical Support in Cardiogenic Shock Complicating Acute Coronary Syndrome: Ready for Prime Time?
- Source :
-
Current vascular pharmacology [Curr Vasc Pharmacol] 2018; Vol. 16 (5), pp. 418-426. - Publication Year :
- 2018
-
Abstract
- Cardiogenic Shock (CS) is a major challenge in current cardiology. Over the last decade, cardiogenic shock mortality has decreased somewhat, but it still remains high, particularly when associated with ischaemic heart disease. The challenges are numerous and include prevention, accurate diagnosis, prompt management and effective therapies to support a failing heart and prevent multi-organ failure. Despite improvements in the care of Acute Coronary Syndrome (ACS), it remains the most common cause of CS. In addition to existing medical therapy, mechanical circulatory support has been proposed for the management of ventricular failure. The intra-aortic balloon pump was amongst the first widely used percutaneous mechanical support devices, and more recently, systems providing a higher level of support have been developed. Although the evidence supporting their use is limited, they have the potential to significantly reduce CS-associated mortality. In this narrative review, we summarize the available evidence and discuss the future directions regarding percutaneous mechanical circulatory support in patients with left ventricular dysfunction and CS complicating ACS.<br /> (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.)
- Subjects :
- Acute Coronary Syndrome mortality
Acute Coronary Syndrome physiopathology
Acute Coronary Syndrome therapy
Extracorporeal Membrane Oxygenation adverse effects
Extracorporeal Membrane Oxygenation mortality
Humans
Intra-Aortic Balloon Pumping adverse effects
Intra-Aortic Balloon Pumping mortality
Prosthesis Design
Recovery of Function
Risk Factors
Shock, Cardiogenic etiology
Shock, Cardiogenic mortality
Shock, Cardiogenic physiopathology
Treatment Outcome
Ventricular Dysfunction, Left etiology
Ventricular Dysfunction, Left mortality
Ventricular Dysfunction, Left physiopathology
Ventricular Function, Left
Acute Coronary Syndrome complications
Extracorporeal Membrane Oxygenation instrumentation
Heart-Assist Devices
Intra-Aortic Balloon Pumping instrumentation
Shock, Cardiogenic therapy
Ventricular Dysfunction, Left therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1875-6212
- Volume :
- 16
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Current vascular pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 29345584
- Full Text :
- https://doi.org/10.2174/1570161116666180116165544