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Me 3 Si-SiMe 2 [oCON(iPr) 2 -C 6 H 4 ]: An Unsymmetrical Disilane Reagent for Regio- and Stereoselective Bis-Silylation of Alkynes.
- Source :
-
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2018 Apr 16; Vol. 57 (17), pp. 4769-4773. Date of Electronic Publication: 2018 Mar 12. - Publication Year :
- 2018
-
Abstract
- The air-stable unsymmetrical disilane Me <subscript>3</subscript> Si-SiMe <subscript>2</subscript> [oCON(iPr) <subscript>2</subscript> C <subscript>6</subscript> H <subscript>4</subscript> ] has been developed for bis-silylation of alkynes. This reagent tolerates a range of functional groups, providing Z-vinyl disilanes in high yields. It is proposed that the phenyl-ring-tethered amide group directs oxidative addition of Pd <superscript>0</superscript> into the Si-Si bond, which might facilitate formation of a six-membered Pd cycle, generating products with good to excellent regioselectivity.<br /> (© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Details
- Language :
- English
- ISSN :
- 1521-3773
- Volume :
- 57
- Issue :
- 17
- Database :
- MEDLINE
- Journal :
- Angewandte Chemie (International ed. in English)
- Publication Type :
- Academic Journal
- Accession number :
- 29442434
- Full Text :
- https://doi.org/10.1002/anie.201800513