A novel dicyanoisophorone based red-emitting fluorescent probe with a large Stokes shift for detection of hydrazine in solution and living cells.

Authors :: Lv H
Sun H
Wang S
Kong F
Source :: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2018 May 05; Vol. 196, pp. 160-167. Date of Electronic Publication: 2018 Feb 08.
Publication Year :: 2018
Abstract: A novel dicyanoisophorone based fluorescent probe HP was developed to detect hydrazine. Upon the addition of hydrazine, probe HP displayed turn-on fluorescence in the red region with a large Stokes shift (180nm). This probe exhibited high selectivity and high sensitivity to hydrazine in solution. The detection limit of HP was found to be 3.26ppb, which was lower than the threshold limit value set by USEPA (10ppb). Moreover, the probe was successfully applied to detect hydrazine in different water samples and living cells.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)

Subjects :: Cyclohexanones chemistry
Dimethyl Sulfoxide
Drug Stability
HeLa Cells
Humans
Hydrazines metabolism
Hydrogen-Ion Concentration
Microscopy, Confocal
Microscopy, Fluorescence
Cytological Techniques methods
Fluorescent Dyes chemistry
Hydrazines analysis
Isocyanates chemistry

Language :: English
ISSN :: 1873-3557
Volume :: 196
Database :: MEDLINE
Journal :: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Publication Type :: Academic Journal
Accession number :: 29444498
Full Text :: https://doi.org/10.1016/j.saa.2018.02.026

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