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Generation of a human iPSC line, IISHDOi002-A, with a 46, XY/47, XYY mosaicism and belonging to an African mitochondrial haplogroup.
- Source :
-
Stem cell research [Stem Cell Res] 2018 Apr; Vol. 28, pp. 131-135. Date of Electronic Publication: 2018 Feb 14. - Publication Year :
- 2018
-
Abstract
- We have generated a human iPSC line, IISHDOi002-A, from commercial primary normal human dermal fibroblasts belonging to an African mitochondrial haplogroup (L3), and with a 46, XY/47, XYY mosaicism. For this purpose, reprogramming factors Oct3/4, Sox2, Klf4 and cMyc were delivered using a non-integrative methodology that involves the use of Sendai virus.<br /> (Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1876-7753
- Volume :
- 28
- Database :
- MEDLINE
- Journal :
- Stem cell research
- Publication Type :
- Academic Journal
- Accession number :
- 29471262
- Full Text :
- https://doi.org/10.1016/j.scr.2018.02.009