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A resumable two-photon fluorescent probe for Cu 2+ and S 2- based on magnetic silica core-shell Fe 3 O 4 @SiO 2 nanoparticles and its application in bioimaging.
- Source :
-
Analytica chimica acta [Anal Chim Acta] 2018 Jul 19; Vol. 1014, pp. 91-99. Date of Electronic Publication: 2018 Feb 10. - Publication Year :
- 2018
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Abstract
- A two-photon fluorescent probe for Cu <superscript>2+</superscript> and S <superscript>2-</superscript> has been strategically prepared with naphthalimide derivative platform (NPE) covalently grafted onto the surface of magnetic core-shell Fe <subscript>3</subscript> O <subscript>4</subscript> @SiO <subscript>2</subscript> nanoparticles. The probe (NPE-Fe <subscript>3</subscript> O <subscript>4</subscript> @SiO <subscript>2</subscript> ) exhibits selective response to Cu <superscript>2+</superscript> with enhanced fluorescence and efficient separation of Cu <superscript>2+</superscript> with external magnetic field. The consequent product NPE-Fe <subscript>3</subscript> O <subscript>4</subscript> @SiO <subscript>2</subscript> -Cu of NPE-Fe <subscript>3</subscript> O <subscript>4</subscript> @SiO <subscript>2</subscript> and Cu <superscript>2+</superscript> can work as an excellent sensor for S <superscript>2-</superscript> by removing Cu <superscript>2+</superscript> from the complex with fluorescence decreased, recovering the fluorescence of the probe. Therefore, the constituted Off-On-Off type fluorescence monitoring system means the probe is resumable. Moreover, the probe has been used to quantitatively detect Cu <superscript>2+</superscript> and S <superscript>2-</superscript> with low detection limits, which are 0.28 μM and 0.12 μM, respectively. Furthermore, the probe shows low cytotoxicity and excellent membrane permeability, which has been successfully applied for monitoring Cu <superscript>2+</superscript> and S <superscript>2-</superscript> in living cells and imaging Cu <superscript>2+</superscript> in deep-tissue with two-photon excited fluorescence.<br /> (Copyright © 2018. Published by Elsevier B.V.)
Details
- Language :
- English
- ISSN :
- 1873-4324
- Volume :
- 1014
- Database :
- MEDLINE
- Journal :
- Analytica chimica acta
- Publication Type :
- Academic Journal
- Accession number :
- 29523257
- Full Text :
- https://doi.org/10.1016/j.aca.2018.02.006