Direct Factor X sequestration by systemic amyloid light-chain amyloidosis.

Authors :: Tashiro H
Shirasaki R
Watanabe M
Kawasugi K
Takahashi Y
Shirafuji N
Source :: Clinical case reports [Clin Case Rep] 2018 Jan 31; Vol. 6 (3), pp. 513-515. Date of Electronic Publication: 2018 Jan 31 (Print Publication: 2018).
Publication Year :: 2018
Abstract: We present a lymphoplasmacytic lymphoma patient with Factor X (FX) deficiency. Despite the absence of FX inhibitor, the administration of fresh frozen plasma and anti-inhibitor coagulant complex did not increase the FX level. The autopsy showed that massive amyloid depositions to multiple organs and FX existed in union with amyloidosis.