Effect of pre-firing compression on the prevention of pancreatic fistula in distal pancreatectomy.

Authors :: Hirashita T
Ohta M
Yada K
Tada K
Saga K
Takayama H
Endo Y
Uchida H
Iwashita Y
Inomata M
Source :: American journal of surgery [Am J Surg] 2018 Sep; Vol. 216 (3), pp. 506-510. Date of Electronic Publication: 2018 Mar 26.
Publication Year :: 2018
Abstract: Background: Postoperative pancreatic fistula (POPF) is a major complication of distal pancreatectomy (DP). Several procedures for resection and closure of the pancreas have been proposed; however, the rate of POPF remains high. The aims of this study were to investigate the relationship between perioperative factors and POPF and to clarify the advantages of pre-firing compression of the pancreas in the DP.<br />Patients and Method: From 2008 to 2016, records of 75 patients who underwent DP were retrospectively reviewed. The relationship between the perioperative factors and clinically relevant POPF was investigated.<br />Results: Univariate analysis showed that body mass index, thickness of the pancreas, and pre-firing compression were significantly related with clinically relevant POPF. Multivariate analysis showed that the pre-firing compression was an independent factor of clinically relevant POPF (OR = 44.31, 95%CI = 3.394-578.3, P = 0.004).<br />Conclusions: Pre-firing compression of the pancreas can prevent clinically relevant POPF in DP.<br /> (Copyright © 2018 Elsevier Inc. All rights reserved.)

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