Back to Search
Start Over
Factor analysis of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis.
- Source :
-
International forum of allergy & rhinology [Int Forum Allergy Rhinol] 2018 Jul; Vol. 8 (7), pp. 777-782. Date of Electronic Publication: 2018 Apr 06. - Publication Year :
- 2018
-
Abstract
- Background: Olfactory-specific quality of life (QOL) can be measured using the Questionnaire of Olfactory Disorders-Negative Statements (QOD-NS), which examines various aspects of olfactory dysfunction. It is unknown if certain factors of the QOD-NS differentially impact QOL.<br />Methods: Patients with chronic rhinosinusitis (CRS) completed the QOD-NS, 22-item Sino-Nasal Outcome Test (SNOT-22), Medical Outcomes Study Short Form 6-D (SF-6D) health utility measure, and Patient Health Questionnaire-2 (PHQ-2) depression screen. Exploratory factor analysis of the QOD-NS was performed. Associations between QOD-NS factors and other QOL metrics were analyzed before and after endoscopic sinus surgery (ESS).<br />Results: Outcomes were examined on 132 patients. The QOD-NS contains 4 distinct factors. There was no difference in associations between the different factors and baseline clinical characteristics. ESS had greatest effect size (d) on factors 2 and 4 (d = 0.29 and 0.27, respectively, p < 0.05). Postsurgical changes in the SF-6D and SNOT-22 had the strongest correlation with factor 2 scores (r = 0.29 and 0.34, respectively, p < 0.05), and changes in the PHQ-2 had the strongest correlation to factor 3 (r = 0.24, p < 0.05). Abnormal QOD-NS scores at baseline were associated with effect size increases of 50% to 100% (p < 0.05).<br />Conclusion: The QOD-NS measures 4 distinct factors. Eating-related questions had the greatest improvement after ESS. Health utility and CRS-specific QOL improvement most strongly associated with factor 2, while PHQ-2 changes are most highly associated with factor 3, suggesting a differential impact of the factors of the QOD-NS on varying aspects of QOL.<br /> (© 2018 ARS-AAOA, LLC.)
- Subjects :
- Adult
Aged
Chronic Disease
Endoscopy
Factor Analysis, Statistical
Female
Humans
Male
Middle Aged
Olfaction Disorders surgery
Paranasal Sinuses surgery
Quality of Life
Rhinitis surgery
Sinusitis surgery
Olfaction Disorders diagnosis
Rhinitis diagnosis
Sinusitis diagnosis
Smell
Surveys and Questionnaires
Subjects
Details
- Language :
- English
- ISSN :
- 2042-6984
- Volume :
- 8
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- International forum of allergy & rhinology
- Publication Type :
- Academic Journal
- Accession number :
- 29633540
- Full Text :
- https://doi.org/10.1002/alr.22112