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Colistin-induced myasthenic syndrome in a patient with end-stage renal disease.
- Source :
-
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia [Saudi J Kidney Dis Transpl] 2018 Mar-Apr; Vol. 29 (2), pp. 435-439. - Publication Year :
- 2018
-
Abstract
- With resurgence of multidrug resistance (MDR) bacteria and no new novel broad-spectrum antibiotic in research pipeline, usage of older generation antibiotics, once discarded due to their toxicity profile are becoming popular again. Often these drugs are the only option left in managing MDR bacteria-related sepsis. Colistin is one of such antibiotic which is often used in recent times after decades of its avoidance due to its diverse toxicity profile. In this case report, we present a rare myasthenic syndrome like neuromuscular complication developed in a patient after receiving colistin for treatment of MDR Klebsiella-related urosepsis.<br />Competing Interests: None declared
- Subjects :
- Drug Resistance, Multiple, Bacterial
Female
Humans
Kidney Failure, Chronic diagnosis
Kidney Failure, Chronic therapy
Klebsiella Infections complications
Klebsiella Infections diagnosis
Klebsiella Infections microbiology
Middle Aged
Muscle Weakness diagnosis
Muscle Weakness physiopathology
Muscle Weakness therapy
Neuromuscular Junction physiopathology
Neuromuscular Junction Diseases diagnosis
Neuromuscular Junction Diseases physiopathology
Neuromuscular Junction Diseases therapy
Recovery of Function
Syndrome
Treatment Outcome
Urinary Tract Infections complications
Urinary Tract Infections diagnosis
Urinary Tract Infections microbiology
Anti-Bacterial Agents adverse effects
Colistin adverse effects
Kidney Failure, Chronic complications
Klebsiella Infections drug therapy
Muscle Weakness chemically induced
Neuromuscular Junction drug effects
Neuromuscular Junction Diseases chemically induced
Urinary Tract Infections drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1319-2442
- Volume :
- 29
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
- Publication Type :
- Academic Journal
- Accession number :
- 29657216
- Full Text :
- https://doi.org/10.4103/1319-2442.229273