Back to Search
Start Over
Paclitaxel-Coated Balloon Angioplasty for Early Restenosis of Central Veins in Hemodialysis Patients: A Single Center Initial Experience.
- Source :
-
Korean journal of radiology [Korean J Radiol] 2018 May-Jun; Vol. 19 (3), pp. 410-416. Date of Electronic Publication: 2018 Apr 06. - Publication Year :
- 2018
-
Abstract
- Objective: To report the results of angioplasty with paclitaxel-coated balloons for the treatment of early restenosis of central veins in hemodialysis patients.<br />Materials and Methods: Sixteen patients (9 men and 7 women; mean age 65.8 ± 14.4 years; range, 40-82 years) with 16 episodes of early restenoses of central veins within 3 months (median patency duration 2.5 months) were enrolled from January 2014 to June 2015. Ten native central veins and 6 intra-stent central veins were treated with double paclitaxel-coated balloons (diameter 6-7 mm) plus a high pressure balloon (diameter 12-14 mm). The study outcomes included procedural success (< 30% residual stenosis) and primary patency of the treated lesion (< 50% angiographic stenosis without re-intervention).<br />Results: Procedural success was achieved in all 16 cases of central vein stenoses. The mean diameter of the central vein was 3.7 ± 2.4 mm before the procedure vs. 11.4 ± 1.8 mm after the initial procedure. There were no procedure-related complications. The mean diameters of the central veins at 6 months and 12 months were 7.8 ± 1.3 mm and 6.9 ± 2.7 mm, respectively. The primary patency rates at 6 months and 12 months were 93.8% and 31.2%, respectively. One patient had significant restenosis of the central vein at 3 months. The median primary patency period was 9 months for paclitaxel-coated balloons and 2.5 months for the last previous procedure with conventional balloons (p < 0.001).<br />Conclusion: In our limited study, paclitaxel-coated balloons seem to improve the patency rate in cases of early restenosis of central veins. However, a further randomized control trial is necessary.
- Subjects :
- Adult
Aged
Aged, 80 and over
Angiography
Angioplasty, Balloon
Brachiocephalic Veins diagnostic imaging
Constriction, Pathologic drug therapy
Female
Humans
Male
Middle Aged
Renal Dialysis
Treatment Outcome
Antineoplastic Agents, Phytogenic therapeutic use
Constriction, Pathologic therapy
Paclitaxel therapeutic use
Renal Insufficiency, Chronic pathology
Subjects
Details
- Language :
- English
- ISSN :
- 2005-8330
- Volume :
- 19
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Korean journal of radiology
- Publication Type :
- Academic Journal
- Accession number :
- 29713218
- Full Text :
- https://doi.org/10.3348/kjr.2018.19.3.410