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Autologous T-cell activation fosters ABT-199 resistance in chronic lymphocytic leukemia: rationale for a combined therapy with SYK inhibitors and anti-CD20 monoclonal antibodies.
- Source :
-
Haematologica [Haematologica] 2018 Oct; Vol. 103 (10), pp. e458-e461. Date of Electronic Publication: 2018 May 10. - Publication Year :
- 2018
- Subjects :
- Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols pharmacology
Female
Humans
Male
Middle Aged
Protein Kinase Inhibitors pharmacology
Rituximab pharmacology
Bridged Bicyclo Compounds, Heterocyclic pharmacology
Drug Resistance, Neoplasm drug effects
Drug Resistance, Neoplasm immunology
Leukemia, Lymphocytic, Chronic, B-Cell drug therapy
Leukemia, Lymphocytic, Chronic, B-Cell enzymology
Leukemia, Lymphocytic, Chronic, B-Cell immunology
Leukemia, Lymphocytic, Chronic, B-Cell pathology
Lymphocyte Activation drug effects
Neoplasm Proteins antagonists & inhibitors
Neoplasm Proteins immunology
Neoplasm Proteins metabolism
Sulfonamides pharmacology
Syk Kinase antagonists & inhibitors
Syk Kinase immunology
Syk Kinase metabolism
T-Lymphocytes immunology
T-Lymphocytes pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1592-8721
- Volume :
- 103
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Haematologica
- Publication Type :
- Report
- Accession number :
- 29748439
- Full Text :
- https://doi.org/10.3324/haematol.2018.188680