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Predictors of falls in older survivors of breast and prostate cancer: A retrospective cohort study of surveillance, epidemiology and end results-Medicare health outcomes survey linkage.
- Source :
-
Journal of geriatric oncology [J Geriatr Oncol] 2019 Jan; Vol. 10 (1), pp. 89-97. Date of Electronic Publication: 2018 May 08. - Publication Year :
- 2019
-
Abstract
- Objectives: To identify predictors of falls in older breast and prostate cancer survivors.<br />Methods: This retrospective cohort study analyzed population-based Surveillance, Epidemiology and End Results-Medicare Health Outcomes Survey (SEER-MHOS) linkage. Inclusion criteria were age >65 years at cancer diagnosis, first primary female breast or prostate cancer, cancer staging information available, completion of baseline MHOS during years 2-3 and follow-up MHOS during years 4-5 post-diagnosis, and falls information available. Data from 437 breast and 660 prostate cancer survivors were analyzed. Multivariable logistic regression was constructed to evaluate variables from baseline MHOS with relation to falls from follow-up MHOS. Model accuracy was assessed using area under receiver-operating-characteristic curve (AUC).<br />Results: At follow-up MHOS, 26% of breast and 22% of prostate cancer survivors reported falls in the past 12 months. In breast cancer, a history of falls (odds ratio (OR) = 4.95, 95% confidence interval (CI) = 2.44-10.04) and sensory impairment in feet (OR = 3.33, 95%CI = 1.51-7.32) were significant predictors of falls. In prostate cancer, a history of falls (OR = 3.04, 95%CI = 1.79-5.15), unmarried (OR = 1.82, 95%CI = 1.12-2.95), lower physical summary score of quality-of-life(OR = 0.96, 95%CI = 0.94-0.98), urinary incontinence (OR = 1.69, 95%CI = 1.08-2.65), older age at diagnosis (OR = 1.05, 95%CI = 1.01-1.09), and shorter time post-diagnosis (OR = 0.96, 95%CI = 0.93-0.99) were significant predictors of falls. AUC was 0.67 and 0.77 for breast and prostate cancer, respectively, indicating moderate accuracy of models in detecting fallers.<br />Conclusions: Asking older breast and prostate cancer survivors about falls in the past 12 months is imperative in fall prevention. Further examination of deficits specific to each cancer is necessary to assess fall risks.<br /> (Copyright © 2018 Elsevier Ltd. All rights reserved.)
- Subjects :
- Accidental Falls prevention & control
Aged
Female
Humans
Male
Marital Status
Medicare statistics & numerical data
Population Surveillance
Retrospective Studies
Risk Factors
SEER Program statistics & numerical data
Socioeconomic Factors
Surveys and Questionnaires
United States
Accidental Falls statistics & numerical data
Breast Neoplasms complications
Cancer Survivors statistics & numerical data
Prostatic Neoplasms complications
Subjects
Details
- Language :
- English
- ISSN :
- 1879-4076
- Volume :
- 10
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of geriatric oncology
- Publication Type :
- Academic Journal
- Accession number :
- 29752141
- Full Text :
- https://doi.org/10.1016/j.jgo.2018.04.009