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Malaria Elimination: Time to Target All Species.
- Source :
-
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2018 Jul; Vol. 99 (1), pp. 17-23. Date of Electronic Publication: 2018 May 10. - Publication Year :
- 2018
-
Abstract
- Important strides have been made within the past decade toward malaria elimination in many regions, and with this progress, the feasibility of eradication is once again under discussion. If the ambitious goal of eradication is to be achieved by 2040, all species of Plasmodium infecting humans will need to be targeted with evidence-based and concerted interventions. In this perspective, the potential barriers to achieving global malaria elimination are discussed with respect to the related diversities in host, parasite, and vector populations. We argue that control strategies need to be reorientated from a sequential attack on each species, dominated by Plasmodium falciparum to one that targets all species in parallel. A set of research themes is proposed to mitigate the potential setbacks on the pathway to a malaria-free world.
- Subjects :
- Animals
Anopheles parasitology
Antimalarials therapeutic use
Chloroquine therapeutic use
Disease Eradication economics
Host-Parasite Interactions
Humans
Malaria drug therapy
Malaria immunology
Malaria parasitology
Malaria, Falciparum drug therapy
Malaria, Falciparum immunology
Malaria, Falciparum parasitology
Malaria, Vivax drug therapy
Malaria, Vivax immunology
Malaria, Vivax parasitology
Mosquito Vectors parasitology
Plasmodium falciparum drug effects
Plasmodium falciparum immunology
Plasmodium falciparum pathogenicity
Plasmodium knowlesi drug effects
Plasmodium knowlesi immunology
Plasmodium knowlesi pathogenicity
Plasmodium malariae drug effects
Plasmodium malariae immunology
Plasmodium malariae pathogenicity
Plasmodium ovale drug effects
Plasmodium ovale immunology
Plasmodium ovale pathogenicity
Plasmodium vivax drug effects
Plasmodium vivax immunology
Plasmodium vivax pathogenicity
Primaquine therapeutic use
Disease Eradication methods
Malaria prevention & control
Malaria, Falciparum prevention & control
Malaria, Vivax prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1476-1645
- Volume :
- 99
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The American journal of tropical medicine and hygiene
- Publication Type :
- Academic Journal
- Accession number :
- 29761762
- Full Text :
- https://doi.org/10.4269/ajtmh.17-0869