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Enterobacteria and host resistance to infection.
- Source :
-
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2018 Aug; Vol. 29 (7-8), pp. 558-576. Date of Electronic Publication: 2018 May 21. - Publication Year :
- 2018
-
Abstract
- Enterobacteriaceae are a large family of Gram-negative, non-spore-forming bacteria. Although many species exist as part of the natural flora of animals including humans, some members are associated with both intestinal and extraintestinal diseases. In this review, we focus on members of this family that have important roles in human disease: Salmonella, Escherichia, Shigella, and Yersinia, providing a brief overview of the disease caused by these bacteria, highlighting the contribution of animal models to our understanding of their pathogenesis and of host genetic determinants involved in susceptibility or resistance to infection.
- Subjects :
- Alleles
Animals
Disease Models, Animal
Enterobacteriaceae Infections genetics
Enterobacteriaceae Infections immunology
Enterobacteriaceae Infections metabolism
Humans
Quantitative Trait Loci
Disease Resistance genetics
Disease Resistance immunology
Disease Susceptibility
Enterobacteriaceae physiology
Enterobacteriaceae Infections microbiology
Host-Pathogen Interactions genetics
Host-Pathogen Interactions immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1432-1777
- Volume :
- 29
- Issue :
- 7-8
- Database :
- MEDLINE
- Journal :
- Mammalian genome : official journal of the International Mammalian Genome Society
- Publication Type :
- Academic Journal
- Accession number :
- 29785663
- Full Text :
- https://doi.org/10.1007/s00335-018-9749-4