Back to Search
Start Over
Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene.
- Source :
-
Journal of virology [J Virol] 1985 Mar; Vol. 53 (3), pp. 984-7. - Publication Year :
- 1985
-
Abstract
- We determined the nucleotide sequence of the v-H-ras-related oncogene of BALB/c murine sarcoma virus. This oncogene contains an open reading frame of 189 amino acids that initiates and terminates entirely within the mouse cell-derived ras sequence. The protein encoded by this open reading frame matches the sequence predicted for the T24 human bladder carcinoma oncogene product, p21, in all but two positions. The presence of a lysine residue in position 12 of BALB/c murine sarcoma virus p21 likely accounts for its oncogenic properties.
Details
- Language :
- English
- ISSN :
- 0022-538X
- Volume :
- 53
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of virology
- Publication Type :
- Academic Journal
- Accession number :
- 2983103
- Full Text :
- https://doi.org/10.1128/JVI.53.3.984-987.1985