Back to Search
Start Over
Misclassification of self-reported smoking in adult survivors of childhood cancer.
- Source :
-
Pediatric blood & cancer [Pediatr Blood Cancer] 2018 Sep; Vol. 65 (9), pp. e27240. Date of Electronic Publication: 2018 Jun 01. - Publication Year :
- 2018
-
Abstract
- We investigated misclassification rates, sensitivity, and specificity of self-reported cigarette smoking through serum cotinine concentration (liquid chromatography tandem mass spectrometry) among 287 adult survivors of childhood cancer. Overall, 2.5-6.7% and 19.7-36.9% of the self-reported never and past smokers had cotinine levels indicative of active smoking. Sensitivity and specificity of self-reported smoking were 57.5-67.1% and 96.6-99.2%. Misclassification was associated with younger age (OR = 3.2; 95% CI = 1.4-7.4), male (OR = 2.1; 95% CI = 1.1-4.0), and past (OR = 2.7; 95% CI = 1.3-5.8) or current (OR = 2.6; 95% CI = 1.0-6.6) marijuana use. After adjusting for tobacco-related variables, current marijuana use remained a significant risk for misclassification. Clinicians/researchers should consider bio-verification to measure smoking status among survivors.<br /> (© 2018 Wiley Periodicals, Inc.)
- Subjects :
- Adolescent
Adult
Biomarkers
Cotinine blood
False Negative Reactions
False Positive Reactions
Female
Humans
Male
Marijuana Smoking blood
Middle Aged
Sensitivity and Specificity
Smoking blood
Smoking psychology
Surveys and Questionnaires
Survivors psychology
Young Adult
Marijuana Smoking epidemiology
Self Report
Smoking epidemiology
Survivors statistics & numerical data
Truth Disclosure
Subjects
Details
- Language :
- English
- ISSN :
- 1545-5017
- Volume :
- 65
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Pediatric blood & cancer
- Publication Type :
- Academic Journal
- Accession number :
- 29856513
- Full Text :
- https://doi.org/10.1002/pbc.27240