Back to Search
Start Over
Addressing the Challenges of Structure Elucidation in Natural Products Possessing the Oxirane Moiety.
- Source :
-
The Journal of organic chemistry [J Org Chem] 2018 Aug 03; Vol. 83 (15), pp. 8341-8352. Date of Electronic Publication: 2018 Jul 10. - Publication Year :
- 2018
-
Abstract
- NMR data for natural products containing the epoxy moiety have been revisited and reanalyzed with the help of a recently developed parametric/DFT hybrid computational method, DU8+. More than 20 structures needed revision, which points to challenges in NMR solution structure assignment for molecules possessing this structural feature. Among the revised structures are achicretin 2, acremine P, aromaticane I, artanomalide B, botryosphaerihydrofuran, chloroklotzchin, crithmifolide, crotodichogamoin A, emervaridone C, 9α,15-epoxyafricanane, fischambiguine B, grandilobalide B, guaianolide A, guatterfriesols A and B, juncenolide G, roscotane D, secoafricane 7, taccalonolides AJ and AF, and related compounds.
Details
- Language :
- English
- ISSN :
- 1520-6904
- Volume :
- 83
- Issue :
- 15
- Database :
- MEDLINE
- Journal :
- The Journal of organic chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 29912559
- Full Text :
- https://doi.org/10.1021/acs.joc.8b01027