Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia.

Authors :: Milani G
Matthijssens F
Van Loocke W
Durinck K
Roels J
Peirs S
Thénoz M
Pieters T
Reunes L
Lintermans B
Vandamme N
Lammens T
Van Roy N
Van Nieuwerburgh F
Deforce D
Schwab C
Raimondi S
Dalla Pozza L
Carroll AJ 3rd
De Moerloose B
Benoit Y
Goossens S
Berx G
Harrison CJ
Basso G
Cavé H
Sutton R
Asnafi V
Meijerink J
Mullighan C
Loh M
Van Vlierberghe P
Source :: British journal of haematology [Br J Haematol] 2019 Apr; Vol. 185 (1), pp. 169-174. Date of Electronic Publication: 2018 Jun 25.
Publication Year :: 2019

Subjects :: Animals
Biomarkers, Tumor
DNA Copy Number Variations
Disease Models, Animal
Genetic Association Studies
Humans
Mice
Molecular Targeted Therapy
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma drug therapy
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma pathology
Translocation, Genetic
Xenograft Model Antitumor Assays
Gene Rearrangement
Genes, myc
Genetic Predisposition to Disease
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma genetics

Full Text Access

Tools