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Antibacterial and antifungal activity of phytosterols and methyl dehydroabietate of Norway spruce bark extracts.

Authors :
Burčová Z
Kreps F
Greifová M
Jablonský M
Ház A
Schmidt Š
Šurina I
Source :
Journal of biotechnology [J Biotechnol] 2018 Sep 20; Vol. 282, pp. 18-24. Date of Electronic Publication: 2018 Jun 22.
Publication Year :
2018

Abstract

The current study focuses on the analysis of in vitro biological activity of extract from bark of Norway spruce (Picea Abies), which can find potential application in food and cosmetic industry and pharmacology. Milled bark was subjected to Soxhlet extraction and supercritical fluid extraction to obtain two ethanol extracts. These extracts were further used to obtain their pre-extracts to n-hexane. It was investigated whether beta-sitosterol exhibits bacteriostatic activity necessary to observe antimicrobial and antifungal activity of methyl dehydroabiatate. This synergic effect and bacteriostatic activity of beta-sitosterol have not been previously reported. The greatest inhibition zone of n-hexane pre-extracts was confirmed in bacterium Pseudomonas aeruginosa (0,9 - 1,5 cm) and yeast Alternaria alternata (0,7 - 1,6 cm). It is novel, the antioxidant, antimicrobial and antifungal activity of spruce bark extracts assessed in terms of food and cosmetic fortification.<br /> (Copyright © 2018 Elsevier B.V. All rights reserved.)

Details

Language :
English
ISSN :
1873-4863
Volume :
282
Database :
MEDLINE
Journal :
Journal of biotechnology
Publication Type :
Academic Journal
Accession number :
29940188
Full Text :
https://doi.org/10.1016/j.jbiotec.2018.06.340