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Prospective Assessment of the Performance of a New Fine Needle Biopsy Device for EUS-Guided Sampling of Solid Lesions.
- Source :
-
Clinical endoscopy [Clin Endosc] 2018 Nov; Vol. 51 (6), pp. 576-583. Date of Electronic Publication: 2018 Jul 13. - Publication Year :
- 2018
-
Abstract
- Background/aims: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) remains the most common EUS-guided tissue acquisition technique. This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUSguided sampling of solid lesions and compare it with the historical FNA technique.<br />Methods: Acquire® 22 G FNB needle (Boston Scientific Co., Natick, MA, USA) was used for solid tumor sampling (Study group). Tissue was collected for rapid on-site evaluation, and touch and crush preparations were made. Historical EUS-FNA samples obtained using Expect® 22 G FNA needle (Boston Scientific Co.) were used as controls (Control group). All specimens were independently evaluated by two cytopathologists blinded to the formal cytopathological diagnosis.<br />Results: Mean cell block histology scores were significantly higher (p=0.046) in the FNB group (51 samples) despite a significantly lower (p<0.001) mean number of passes compared to the FNA group (50 specimens). The overall diagnostic yields for the FNB vs. FNA groups were 96% vs. 88%. The degree of tumor differentiation was adequately assessed in all cell block qualifying lesions in the FNB group. Two patients developed post-FNB abdominal pain.<br />Conclusion: The new Franseen tip FNB device provides histologically superior and cytologically comparable specimens to those obtained by FNA, but with fewer passes.
Details
- Language :
- English
- ISSN :
- 2234-2400
- Volume :
- 51
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Clinical endoscopy
- Publication Type :
- Academic Journal
- Accession number :
- 30001616
- Full Text :
- https://doi.org/10.5946/ce.2018.053