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Effect of embryo and blastocyst transfer on the birthweight of live-born singletons from FET cycles.
- Source :
-
Journal of assisted reproduction and genetics [J Assist Reprod Genet] 2018 Oct; Vol. 35 (10), pp. 1905-1910. Date of Electronic Publication: 2018 Jul 20. - Publication Year :
- 2018
-
Abstract
- Purpose: To evaluate the effect of culture duration (embryo (day 3) transfer vs. blastocyst (day 5-6) transfer) on the birthweight of singletons from frozen embryo transfer (FET) cycles.<br />Methods: A total of 1092 singletons were analyzed in this retrospective study. The distribution of large for gestational age (LGA) infants, the mean birthweight, and z scores of singletons were compared between the day 3 and day 5-6 transfer groups. Multiple linear regression analysis was performed to evaluate the relationships between confounding factors and singleton birthweight.<br />Results: The proportion of LGA infants significantly increased with BMI (BMI < 20, 12.8%; 20 ≤ BMI ≤ 25, 23.2%; BMI > 25, 32.3%; P < 0.0001). However, the proportions of small for gestational age (SGA) and LGA infants were not significantly different between day 3 and day 5-6 transfers. The absolute mean birthweight of singletons was not significantly different between day 3 transfer (3422 ± 547 g) and day 5-6 transfer (3433 ± 559 g; P = 0.732). The z scores (calculated from a reference population) of singletons were also not significantly different between the two groups (0.499 vs. 0.533, P = 0.625). Multiple linear regression analysis showed that maternal BMI, gestational age, and infant gender had significant effects on singleton birthweight, while culture duration (P = 0.731) did not significantly affect singleton birthweight.<br />Conclusions: In vitro culture duration did not affect the birthweight of newborns resulting from day 3 to day 5-6 transfers in FET cycles.
Details
- Language :
- English
- ISSN :
- 1573-7330
- Volume :
- 35
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Journal of assisted reproduction and genetics
- Publication Type :
- Academic Journal
- Accession number :
- 30030709
- Full Text :
- https://doi.org/10.1007/s10815-018-1257-7