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MDM2 controls gene expression independently of p53 in both normal and cancer cells.
- Source :
-
Cell death and differentiation [Cell Death Differ] 2018 Sep; Vol. 25 (9), pp. 1533-1535. Date of Electronic Publication: 2018 Jul 23. - Publication Year :
- 2018
- Subjects :
- Animals
DNA Damage
Genomic Instability
Humans
Mice
Mice, Knockout
NADH Dehydrogenase genetics
NADH Dehydrogenase metabolism
Neoplasms metabolism
Proto-Oncogene Proteins c-mdm2 genetics
RNA Stability
Tumor Suppressor Protein p53 genetics
Ubiquitination
Gene Expression Regulation
Neoplasms pathology
Proto-Oncogene Proteins c-mdm2 metabolism
Tumor Suppressor Protein p53 metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1476-5403
- Volume :
- 25
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Cell death and differentiation
- Publication Type :
- Academic Journal
- Accession number :
- 30038384
- Full Text :
- https://doi.org/10.1038/s41418-018-0156-x