Back to Search
Start Over
Accelerated magnetic resonance fingerprinting using soft-weighted key-hole (MRF-SOHO).
- Source :
-
PloS one [PLoS One] 2018 Aug 09; Vol. 13 (8), pp. e0201808. Date of Electronic Publication: 2018 Aug 09 (Print Publication: 2018). - Publication Year :
- 2018
-
Abstract
- Object: To develop a novel approach for highly accelerated Magnetic Resonance Fingerprinting (MRF) acquisition.<br />Materials and Methods: The proposed method combines parallel imaging, soft-gating and key-hole approaches to highly accelerate MRF acquisition. Slowly varying flip angles (FA), commonly used during MRF acquisition, lead to a smooth change in the signal contrast of consecutive time-point images. This assumption enables sharing of high frequency data between different time-points, similar to what is done in some dynamic MR imaging methods such as key-hole. The proposed approach exploits this information using a SOft-weighted key-HOle (MRF-SOHO) reconstruction to achieve high acceleration factors and/or increased resolution without compromising image quality or increasing scan time. MRF-SOHO was validated on a standard T1/T2 phantom and in in-vivo brain acquisitions reconstructing T1, T2 and proton density parametric maps.<br />Results: Accelerated MRF-SOHO using less data per time-point and less time-point images enabled a considerable reduction in scan time (up to 4.6x), while obtaining similar T1 and T2 accuracy and precision when compared to zero-filled MRF reconstruction. For the same number of spokes and time-points, the proposed method yielded an enhanced performance in quantifying parameters than the zero-filled MRF reconstruction, which was verified with 2, 1 and 0.7 (sub-millimetre) resolutions.<br />Conclusion: The proposed MRF-SOHO enabled a 4.6x scan time reduction for an in-plane spatial resolution of 2x2 mm2 when compared to zero-filled MRF and enabled sub-millimetric (0.7x0.7 mm2) resolution MRF.<br />Competing Interests: One of the co-authors (Torben Schneider) is an employee of Philips Healthcare. Following the regulation on Competing Interests Statement, I confirm that this does not alter our adherence to PLOS ONE policies on sharing data and materials.
Details
- Language :
- English
- ISSN :
- 1932-6203
- Volume :
- 13
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- PloS one
- Publication Type :
- Academic Journal
- Accession number :
- 30092033
- Full Text :
- https://doi.org/10.1371/journal.pone.0201808