Contradictory results of serological confirmatory test and real-time PCR assays in diagnosis a patient of HIV-1 infection.

Authors :: Shen L
Liu X
Wang T
Yang J
Wu X
Mao L
Source :: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2018 Sep; Vol. 74, pp. 38-40. Date of Electronic Publication: 2018 Jul 06.
Publication Year :: 2018
Abstract: Human immunodeficiency virus (HIV)/AIDS is a major public health problem worldwide. Here we report the case of a patient with positive HIV-1 serology and negative result of The COBAS AmpliPrep/COBAS Taqman HIV-1 Test version 2.0 (CAP/CTM v2.0) assay (Roche Diagnostics) for HIV-1 RNA quantification in the absence of antiretroviral therapy (ARV). Considering the HIV contact history and repeating serological confirmatory test is essential before considering a low or even undetectable HIV-1 viral load to be a false-negative result.<br /> (Copyright © 2018. Published by Elsevier Ltd.)

Subjects :: Adult
Antibodies, Viral blood
Female
HIV Infections blood
HIV Infections virology
HIV-1 genetics
HIV-1 immunology
HIV-1 physiology
Humans
RNA, Viral genetics
Sensitivity and Specificity
Viral Load
HIV Infections diagnosis
HIV-1 isolation & purification
Real-Time Polymerase Chain Reaction methods
Serologic Tests methods

Language :: English
ISSN :: 1878-3511
Volume :: 74
Database :: MEDLINE
Journal :: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Publication Type :: Academic Journal
Accession number :: 30100534
Full Text :: https://doi.org/10.1016/j.ijid.2018.07.001

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