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Poor patient compliance with instructions for continuous sialogogues after 131 I therapy.
- Source :
-
Oral diseases [Oral Dis] 2019 Jan; Vol. 25 (1), pp. 158-163. Date of Electronic Publication: 2018 Sep 19. - Publication Year :
- 2019
-
Abstract
- Objectives: To analyze the role of patient compliance as a factor in evaluating the effectiveness of continuous sialogogues to prevent salivary side effects from <superscript>131</superscript> I therapy in differentiated thyroid cancer patients.<br />Methods: Differentiated thyroid cancer patients who were clinically scheduled for an <superscript>131</superscript> I therapy at MedStar Washington Hospital Center between 2012 and 2013 were given instructions for continuous sialogogues per standard clinical protocol. The prospective survey was given at multiple time points.<br />Results: Ninety-nine patients consented to participate of whom 94 participants had complete data. The mean prescribed <superscript>131</superscript> I activity was 121 ± 50 mCi (4.5 ± 1.9 GBq), range 27.5-288 mCi (1.0-10.7 GBq ). Overall, only 10% (9/94) of patients were compliant with continuous sialogogues. Even though all patients took sialogogues on the first day of post-therapy, 17% of participants did not continuously take sialogogues during the first day, 60% during the first night, and 72% on the second day despite rigorous instructions to continue for two days.<br />Conclusion: Despite repetitive instructions to use sialogogues continuously, most patients (90%) were not compliant. In future studies, strict monitoring and evaluation of patient compliance will be crucial when assessing the effect of continuous versus intermittent or delayed initiation of sialogogues.<br /> (© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.)
- Subjects :
- Adult
Aged
Female
Humans
Iodine Radioisotopes therapeutic use
Male
Middle Aged
Prospective Studies
Sialadenitis etiology
Surveys and Questionnaires
Thyroid Neoplasms complications
Xerostomia etiology
Medication Adherence
Salivation drug effects
Sialadenitis drug therapy
Thyroid Neoplasms radiotherapy
Xerostomia drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1601-0825
- Volume :
- 25
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Oral diseases
- Publication Type :
- Academic Journal
- Accession number :
- 30169900
- Full Text :
- https://doi.org/10.1111/odi.12969