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Gestational diabetes and postnatal depressive symptoms: A prospective cohort study in Western China.
- Source :
-
Women and birth : journal of the Australian College of Midwives [Women Birth] 2019 Jun; Vol. 32 (3), pp. e427-e431. Date of Electronic Publication: 2018 Sep 06. - Publication Year :
- 2019
-
Abstract
- Background: Gestational diabetes mellitus (GDM) can lead to adverse birth outcomes, but its effect on postnatal depression has not been thoroughly investigated, especially in Asian populations.<br />Aim: To determine the prospective association between GDM and postnatal depressive symptoms in Western China.<br />Methods: A prospective cohort study of 1449 mothers was conducted in Chengdu, capital city of Sichuan Province. GDM was diagnosed during pregnancy using oral glucose tolerance tests. Maternal depressive symptoms were measured at 32-37weeks of gestation, then at one and three months after giving birth using a validated Chinese version of the Edinburgh Postnatal Depression Scale (EPDS). Associations between the postnatal EPDS scores, GDM status and blood glucose levels were assessed by multivariable mixed-effects regression models, accounting for baseline EPDS scores of the cohort and other confounding factors.<br />Findings: Compared to the non-GDM group (n=1220), women with GDM (n=229, 15.8%) reported significantly higher mean EPDS scores at both 1-month (p=0.02) and 3-month (p<0.01) postpartum. Similarly, high levels of fasting, 1-h and 2-h blood glucose levels during pregnancy were associated with increased EPDS scores. Mixed-effects models further confirmed the positive association between GDM status and postnatal depressive symptoms, even though the mean EPDS scores decreased substantially over the three time points.<br />Conclusion: Chinese women with GDM were more susceptible to postnatal depression than others without the condition, despite their depressive symptoms reducing over time after childbirth. It is thus important to raise awareness of postnatal depression amongst healthcare professionals who care for women with GDM.<br /> (Copyright © 2018 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.)
- Subjects :
- Adult
Asian People statistics & numerical data
China epidemiology
Cohort Studies
Depression diagnosis
Depression psychology
Depression, Postpartum diagnosis
Depression, Postpartum psychology
Diabetes, Gestational diagnosis
Female
Humans
Postpartum Period
Pregnancy
Prospective Studies
Psychiatric Status Rating Scales
Risk Factors
Young Adult
Asian People psychology
Depression ethnology
Depression, Postpartum ethnology
Diabetes, Gestational ethnology
Diabetes, Gestational psychology
Mothers psychology
Pregnant Women psychology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-1799
- Volume :
- 32
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Women and birth : journal of the Australian College of Midwives
- Publication Type :
- Academic Journal
- Accession number :
- 30196993
- Full Text :
- https://doi.org/10.1016/j.wombi.2018.08.171