Anticoagulants: Pharmacokinetics, Mechanisms of Action, and Indications.

Authors :: DeWald TA
Washam JB
Becker RC
Source :: Neurosurgery clinics of North America [Neurosurg Clin N Am] 2018 Oct; Vol. 29 (4), pp. 503-515. Date of Electronic Publication: 2018 Jul 23.
Publication Year :: 2018
Abstract: Anticoagulant medications are used widely for a variety of medical and surgical diseases, disorders, and conditions associated with thrombosis and thromboembolism. This review highlights labeled indications, mechanisms of action, potential drug interactions, and specific pharmacokinetic characteristics of available anticoagulants as an essential foundation for guiding selection and management of therapies for patients undergoing neurosurgical procedures.<br /> (Copyright © 2018 Elsevier Inc. All rights reserved.)