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Genetic studies of low abundance human plasma proteins. III. Polymorphism of the C1R subcomponent of the first complement component.

Authors :
Kamboh MI
Ferrell RE
Source :
American journal of human genetics [Am J Hum Genet] 1986 Dec; Vol. 39 (6), pp. 826-31.
Publication Year :
1986

Abstract

Genetic polymorphism of the C1R subcomponent of human complement component C1 has been detected in normal plasma samples using the high resolving power of isoelectric focusing in 6 M urea followed by immunoblotting. There are two common alleles at the C1R structural locus that show autosomal codominant inheritance. The C1R*1 and C1R*2 allele frequencies in U.S. white and U.S. black blood donors are: .934, .066, and .899, .101, respectively.

Details

Language :
English
ISSN :
0002-9297
Volume :
39
Issue :
6
Database :
MEDLINE
Journal :
American journal of human genetics
Publication Type :
Academic Journal
Accession number :
3026176