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Blue laser imaging: a new image-enhanced endoscopy for the diagnosis of colorectal lesions.
- Source :
-
European journal of gastroenterology & hepatology [Eur J Gastroenterol Hepatol] 2018 Dec; Vol. 30 (12), pp. 1514-1520. - Publication Year :
- 2018
-
Abstract
- Background: Image-enhanced endoscopy enables real-time differential diagnosis of colorectal lesions through the observation of microvascular architecture.<br />Purpose: To evaluate the efficacy of using blue laser imaging (BLI) for capillary pattern analysis in the differential diagnosis of neoplastic and non-neoplastic lesions.<br />Patients and Methods: This prospective study included 920 consecutive superficial lesions diagnosed in 457 patients. The capillary pattern was analysed using BLI-bright magnification on the basis of the Teixeira classification. Histopathology was used as the reference standard.<br />Results: The adenoma detection rate was 42.3%, with a mean of 0.95 adenomas per patient. Neoplastic lesions were predominant (70.3%), of which 33 (5.1%) had advanced histology. Neoplastic progression was significantly increased in patients aged at least 50 years, in lesions at least 10 mm and in lesions located in the right colon (P<0.01). BLI-based capillary pattern analysis showed 95.5% accuracy, 95.7% sensitivity, 95.2% specificity, 97.9% positive predictive value and 90.3% negative predictive value in the diagnosis of neoplastic lesions. For 672 diminutive lesions (≤5 mm), BLI-based capillary pattern analysis showed 95.7% accuracy, 96.6% sensitivity, 93.6% specificity, 97.2% positive predictive value and 92.2% negative predictive value. Analysing only lesions up to 5 mm in the rectum and sigmoid colon, the values were 95.2, 93.9, 96.5, 95.8 and 94.8%, respectively.<br />Conclusion: BLI associated with magnification yielded excellent results for the real-time predictive histological diagnosis of colorectal lesions.
- Subjects :
- Adult
Aged
Capillaries pathology
Colorectal Neoplasms blood supply
Colorectal Neoplasms pathology
Cross-Sectional Studies
Diagnosis, Differential
Female
Humans
Image Enhancement methods
Lasers
Male
Middle Aged
Narrow Band Imaging
Neovascularization, Pathologic diagnosis
Predictive Value of Tests
Sensitivity and Specificity
Colonoscopy methods
Colorectal Neoplasms diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1473-5687
- Volume :
- 30
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- European journal of gastroenterology & hepatology
- Publication Type :
- Academic Journal
- Accession number :
- 30281534
- Full Text :
- https://doi.org/10.1097/MEG.0000000000001278