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Better Safe than Sorry: A Dual-Function Viral Protein Inhibiting Host Defense.
- Source :
-
Cell host & microbe [Cell Host Microbe] 2018 Oct 10; Vol. 24 (4), pp. 467-469. - Publication Year :
- 2018
-
Abstract
- Viruses employ intricate means to evade host innate immune systems. In this issue of Cell Host & Microbe, Nayak et al. (2018) demonstrate that the cricket paralysis virus (CrPV) protein CrPV-1A blocks host defense through a dual mechanism: directly inhibiting Argonaute2 (Ago2) and simultaneously targeting Ago2 for proteasomal degradation.<br /> (Copyright © 2018 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1934-6069
- Volume :
- 24
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Cell host & microbe
- Publication Type :
- Academic Journal
- Accession number :
- 30308151
- Full Text :
- https://doi.org/10.1016/j.chom.2018.09.012