Morphology-Preferable MoSe 2 Nanobrooms as a Sensing Platform for Highly Selective Apta-Capturing of Salmonella Bacteria.

The present report employed nanobroom (NB)-shaped two-dimensional molybdenum diselenide (MoSe ₂ ) for the preparation of a sensing matrix for the detection of Salmonella paratyphi . An aptamer specific to salmonella was immobilized onto MoSe ₂ NB-modified fluorine-doped tin oxide via glutaraldehyde cross-linking. Structural and morphological characterizations were performed using UV-vis spectroscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction techniques. Characterizations confirmed the nanobroom morphology and nanosize of the MoSe ₂ material. Electrochemical studies revealed a good linear detection range of 10 ^-2 -10 ^-10 CFU/mL with low detection limit of 1 × 10 ^-10 CFU/mL and with R ² = 0.98. The developed preferable nanobroom-shaped sensing matrix can provide a promising platform for rapid and accurate detection of Salmonella in real samples due to its tremendous stability and sensitivity.
Competing Interests: The authors declare no competing financial interest.