Back to Search Start Over

A New Neolignan Glycoside from Vetiveria zizanioides Roots.

Authors :
Matsuo Y
Ohba C
Maeda S
Fukaya H
Mimaki Y
Source :
Natural product communications [Nat Prod Commun] 2016 Jul; Vol. 11 (7), pp. 983-985.
Publication Year :
2016

Abstract

A new neolignan glycoside (1) and four known aromatic compounds (2-5) were isolated. from the roots of Vetiveria zizanioides. The structure of compound 1 was determined based on spectroscopic analysis and hydrolysis. The structure of known flavonoid glycoside 3 was confirmed by X-ray crystallography. Compound 5 showed weak cytotoxic activity against HL-60 cells with an IC₅₀ value of 13.1 ± 0.04 μM.

Subjects

Subjects :
Antineoplastic Agents, Phytogenic chemistry
Antineoplastic Agents, Phytogenic pharmacology
Glycosides classification
HL-60 Cells
Humans
Models, Molecular
Molecular Structure
Plant Oils chemistry
Chrysopogon chemistry
Glycosides chemistry
Plant Roots chemistry

Details

Language :
English
ISSN :
1934-578X
Volume :
11
Issue :
7
Database :
MEDLINE
Journal :
Natural product communications
Publication Type :
Academic Journal
Accession number :
30452177

Tools

Authors Abstract Subjects Details