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A sexual rejection peptide: potential use for controlling mouse overpopulation.
- Source :
-
Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2019 Apr; Vol. 83 (4), pp. 705-708. Date of Electronic Publication: 2018 Dec 05. - Publication Year :
- 2019
-
Abstract
- Exocrine gland-secreting peptide 22 (ESP22) is a 10-kDa protein secreted in tears of juvenile mice. ESP22 inhibits sexual behaviors in adults, leading to a reduction in reproduction rate. We herein identified the 24 amino acid sequence within ESP22 that was essential for exhibiting sexual rejection activity. This synthesizable peptide can be useful for controlling mouse overpopulation.
- Subjects :
- Amino Acid Sequence
Animals
Female
Gene Expression
Intercellular Signaling Peptides and Proteins
Male
Mice
Mice, Inbred C57BL
Olfactory Bulb cytology
Olfactory Bulb drug effects
Olfactory Bulb physiology
Pheromones biosynthesis
Pheromones chemistry
Pheromones pharmacology
Population Density
Proteins genetics
Proteins metabolism
Sensory Receptor Cells cytology
Sensory Receptor Cells drug effects
Sensory Receptor Cells physiology
Sequence Alignment
Tears chemistry
Vomeronasal Organ cytology
Vomeronasal Organ drug effects
Vomeronasal Organ physiology
Pheromones genetics
Population Control methods
Reproduction drug effects
Sexual Behavior, Animal drug effects
Tears metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1347-6947
- Volume :
- 83
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Bioscience, biotechnology, and biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 30516446
- Full Text :
- https://doi.org/10.1080/09168451.2018.1554427