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Medication Management Capacity and Its Neurocognitive Correlates in Huntington's Disease.

Authors :
Sumida CA
Van Etten EJ
Lopez FV
Sheppard DP
Pirogovsky-Turk E
Corey-Bloom J
Filoteo JV
Woods SP
Gilbert PE
Schmitter-Edgecombe M
Source :
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists [Arch Clin Neuropsychol] 2019 Oct 24; Vol. 34 (7), pp. 1121-1126.
Publication Year :
2019

Abstract

Objective: Although medication management is a necessary daily activity for individuals with Huntington's disease (HD), medication management abilities and their relation to cognitive functioning have not been evaluated.<br />Method: Twenty individuals with HD and 20 healthy adults (HA) completed the Medication Management Abilities Assessment (MMAA). Individuals with HD also completed a self-report medication management measure and neuropsychological tests assessing executive function, retrospective memory, and prospective memory.<br />Results: Individuals with HD performed significantly poorer and made more undertaking errors on the MMAA as compared to HA. No group differences were found in overtaking errors. In the HD group, significant associations were found between undertaking errors and perceived medication management ability as well as between MMAA task performance and measures assessing prospective memory and executive functions.<br />Conclusions: Medication management capacity was negatively affected in individuals with HD and may be associated with difficulty remembering to take medications in the future.<br /> (© The Author(s) 2018. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)

Details

Language :
English
ISSN :
1873-5843
Volume :
34
Issue :
7
Database :
MEDLINE
Journal :
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists
Publication Type :
Academic Journal
Accession number :
30517595
Full Text :
https://doi.org/10.1093/arclin/acy093