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A diagnostic strategy for breast calcifications based on a long-term follow-up of 615 lesions.
- Source :
-
Japanese journal of radiology [Jpn J Radiol] 2019 Mar; Vol. 37 (3), pp. 237-244. Date of Electronic Publication: 2018 Dec 19. - Publication Year :
- 2019
-
Abstract
- Purpose: To clarify the long-term outcomes of breast calcifications after stereotactic vacuum-assisted breast biopsy (SVAB) and to develop strategy after SVAB.<br />Methods: Subject comprised 594 patients with 615 calcifications who underwent SVAB. 371 (60.3%) lesions were diagnosed as benign, 38 (6.2%) as indeterminate, and 206 (33.5%) as malignant. We retrospectively reviewed post-biopsy courses of non-malignant lesions which were followed. A histopathological review was performed for false negatives to clarify the reasons.<br />Results: Of the 308 patients with benign lesions, with a median follow-up time of 55.8 months, re-biopsy was performed for 11 (3.6%) due to changes of imaging, and 4 (1.3%) were diagnosed as breast cancer. Of the 36 patients with indeterminate lesion, re-biopsy was performed for 16 (44.4%), and 8 (22.2%) were diagnosed as breast cancer, while 20 (55.6%) showed no changes in imaging with a median follow-up time of 91.7 months without re-biopsy. Weak atypism of intraductal carcinoma may cause a false-negative diagnosis in SVAB for breast calcifications.<br />Conclusions: When SVAB results in non-malignant, patients may be followed by annual screening, while re-biopsy needs to be performed for the patients with a discordant result of SVAB and with changes in an imaging finding during a follow-up.
- Subjects :
- Adult
Aged
Aged, 80 and over
Biopsy, Needle methods
Breast diagnostic imaging
Breast pathology
Breast Diseases diagnostic imaging
Breast Diseases pathology
Diagnosis, Differential
Female
Follow-Up Studies
Humans
Image-Guided Biopsy methods
Middle Aged
Retrospective Studies
Stereotaxic Techniques
Time
Vacuum
Young Adult
Breast Neoplasms diagnostic imaging
Breast Neoplasms pathology
Calcinosis diagnostic imaging
Calcinosis pathology
Mammography methods
Subjects
Details
- Language :
- English
- ISSN :
- 1867-108X
- Volume :
- 37
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Japanese journal of radiology
- Publication Type :
- Academic Journal
- Accession number :
- 30569402
- Full Text :
- https://doi.org/10.1007/s11604-018-0803-7