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Clinical Implications of Incidental Sinonasal Positive FDG Uptake on PET-CT.
- Source :
-
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [Otolaryngol Head Neck Surg] 2019 Apr; Vol. 160 (4), pp. 729-733. Date of Electronic Publication: 2019 Jan 01. - Publication Year :
- 2019
-
Abstract
- Objectives: Fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) has been increasingly used in the past decade. Incidental FDG-avid findings are encountered in these studies, several of which with clinical significance. However, the significance of incidental FDG-avid sinonasal findings has not been studied to date.<br />Study Design: Retrospective cohort study.<br />Setting: A single tertiary medical center.<br />Materials and Methods: The medical records were reviewed of patients with incidental sinonasal positive FDG uptake between 2007 and 2016 who referred for further otolaryngological diagnostic workup.<br />Results: A total of 26 patients were identified, all of whom underwent a diagnostic surgical procedure. Histopathology revealed chronic inflammation (n = 12, 46.1%), malignancy (n = 7, 26.9%), inverted papilloma (n = 4, 15.5%), and fungal infections (n = 3, 11.5%). A unilateral maxillary sinus with FDG uptake was documented for 16 (61.5%) patients. CT evidence of bilateral disease and mucosal or sinus wall thickening correlated with inflammatory disease.<br />Conclusions: Incidental lesions with positive FDG uptake in the sinonasal cavities are at a high risk (40%) of being neoplastic. A diagnostic biopsy is advocated in these cases.
- Subjects :
- Adult
Aged
Aged, 80 and over
Female
Humans
Lymphoma metabolism
Male
Middle Aged
Papilloma, Inverted metabolism
Paranasal Sinus Diseases metabolism
Paranasal Sinus Diseases pathology
Positron Emission Tomography Computed Tomography
Retrospective Studies
Fluorodeoxyglucose F18 pharmacokinetics
Incidental Findings
Lymphoma diagnosis
Papilloma, Inverted diagnosis
Paranasal Sinus Diseases diagnostic imaging
Radiopharmaceuticals pharmacokinetics
Subjects
Details
- Language :
- English
- ISSN :
- 1097-6817
- Volume :
- 160
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 30598053
- Full Text :
- https://doi.org/10.1177/0194599818821862