Back to Search
Start Over
Impact of lymph node sampling on survival in cN0 major salivary gland adenoid cystic carcinoma.
- Source :
-
Head & neck [Head Neck] 2019 Jun; Vol. 41 (6), pp. 1903-1907. Date of Electronic Publication: 2019 Jan 08. - Publication Year :
- 2019
-
Abstract
- Background: The role of elective neck dissection in the management of major salivary gland adenoid cystic carcinoma is unclear.<br />Methods: Data were retrospectively extracted from the National Cancer Center Database. The study cohort included 1504 patients with adenoid cystic carcinoma of major salivary glands with clinical N0 necks who were treated with surgery between 2004 and 2014. The cohort was divided into four groups based on number of lymph nodes (LNs) examined on pathology: 0, 1-8, 9-17, and ≥18 LNs.<br />Results: The rate of occult nodal metastasis was 9.0%. Number of LNs removed was not associated with survival (Reference, 0 LNs; HR = 0.98, 95% CI 0.73-1.32 for 1-8 LNs; HR = 1.22, 95% CI 0.80-1.88 for 9-17 LNs; HR = 0.94, 95% CI 0.61-1.46 for ≥18 LNs) after adjusting for important covariates.<br />Conclusions: LN sampling is not associated with survival in cN0 major salivary gland ACC.<br /> (© 2019 Wiley Periodicals, Inc.)
- Subjects :
- Adult
Aged
Carcinoma, Adenoid Cystic surgery
Female
Humans
Lymphatic Metastasis
Male
Middle Aged
Neoplasm Staging
Retrospective Studies
Salivary Gland Neoplasms surgery
Survival Rate
Carcinoma, Adenoid Cystic mortality
Carcinoma, Adenoid Cystic pathology
Lymph Node Excision
Salivary Gland Neoplasms mortality
Salivary Gland Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1097-0347
- Volume :
- 41
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Head & neck
- Publication Type :
- Academic Journal
- Accession number :
- 30620437
- Full Text :
- https://doi.org/10.1002/hed.25628