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The importance of synthetic chemistry in the pharmaceutical industry.

Authors :
Campos KR
Coleman PJ
Alvarez JC
Dreher SD
Garbaccio RM
Terrett NK
Tillyer RD
Truppo MD
Parmee ER
Source :
Science (New York, N.Y.) [Science] 2019 Jan 18; Vol. 363 (6424).
Publication Year :
2019

Abstract

Innovations in synthetic chemistry have enabled the discovery of many breakthrough therapies that have improved human health over the past century. In the face of increasing challenges in the pharmaceutical sector, continued innovation in chemistry is required to drive the discovery of the next wave of medicines. Novel synthetic methods not only unlock access to previously unattainable chemical matter, but also inspire new concepts as to how we design and build chemical matter. We identify some of the most important recent advances in synthetic chemistry as well as opportunities at the interface with partner disciplines that are poised to transform the practice of drug discovery and development.<br /> (Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.)

Details

Language :
English
ISSN :
1095-9203
Volume :
363
Issue :
6424
Database :
MEDLINE
Journal :
Science (New York, N.Y.)
Publication Type :
Academic Journal
Accession number :
30655413
Full Text :
https://doi.org/10.1126/science.aat0805