Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report.

Authors :: Elias NS
Riedl J
Stouten K
Levin MD
Wolfhagen F
Eefting M
Vermeer HJ
Source :: Clinical case reports [Clin Case Rep] 2018 Dec 04; Vol. 7 (1), pp. 175-179. Date of Electronic Publication: 2018 Dec 04 (Print Publication: 2019).
Publication Year :: 2018
Abstract: Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs-negative hemolytic anemia combined with an increased LDH = Lactate dehydrogenase level are signs to test for PNH. Follow-up does not need any microscopic review's only flow cytometric PNH clone size.

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