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[Progress on the Study of PD-L1 Detection Methods in Non-small Cell Lung Cancer].

Authors :
Guo X
Cao H
Zhou J
Zhou J
Source :
Zhongguo fei ai za zhi = Chinese journal of lung cancer [Zhongguo Fei Ai Za Zhi] 2019 Jan 20; Vol. 22 (1), pp. 40-44.
Publication Year :
2019

Abstract

PD-1/PD-L1 inhibitors play an important role in the first-line and second-line treatment of non-small cell lung cancer (NSCLC), indicating a new treatment strategy of NSCLC. Completed clinical trials have shown that effective detection of PD-L1 expression is the key to the use of immunosuppressive agents. However, the gold standard for PD-L1 detection has still lacked. In recent years, immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA) have been continuously innovated, which accounts for good prospect in PD-L1 detection. The research progress of PD-L1 detection methods in NSCLC is summarized in this review.
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Details

Language :
Chinese
ISSN :
1999-6187
Volume :
22
Issue :
1
Database :
MEDLINE
Journal :
Zhongguo fei ai za zhi = Chinese journal of lung cancer
Publication Type :
Academic Journal
Accession number :
30674392
Full Text :
https://doi.org/10.3779/j.issn.1009-3419.2019.01.08