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[Progress on the Study of PD-L1 Detection Methods in Non-small Cell Lung Cancer].
- Source :
-
Zhongguo fei ai za zhi = Chinese journal of lung cancer [Zhongguo Fei Ai Za Zhi] 2019 Jan 20; Vol. 22 (1), pp. 40-44. - Publication Year :
- 2019
-
Abstract
- PD-1/PD-L1 inhibitors play an important role in the first-line and second-line treatment of non-small cell lung cancer (NSCLC), indicating a new treatment strategy of NSCLC. Completed clinical trials have shown that effective detection of PD-L1 expression is the key to the use of immunosuppressive agents. However, the gold standard for PD-L1 detection has still lacked. In recent years, immunohistochemistry (IHC) and enzyme-linked immunosorbent assay (ELISA) have been continuously innovated, which accounts for good prospect in PD-L1 detection. The research progress of PD-L1 detection methods in NSCLC is summarized in this review. .
- Subjects :
- Carcinoma, Non-Small-Cell Lung diagnosis
Humans
Lung Neoplasms diagnosis
Reproducibility of Results
Sensitivity and Specificity
B7-H1 Antigen analysis
Biomarkers, Tumor analysis
Carcinoma, Non-Small-Cell Lung metabolism
Enzyme-Linked Immunosorbent Assay methods
Immunohistochemistry methods
Lung Neoplasms metabolism
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1999-6187
- Volume :
- 22
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Zhongguo fei ai za zhi = Chinese journal of lung cancer
- Publication Type :
- Academic Journal
- Accession number :
- 30674392
- Full Text :
- https://doi.org/10.3779/j.issn.1009-3419.2019.01.08