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Multidisciplinary intervention to improve medication safety in nursing home residents: protocol of a cluster randomised controlled trial (HIOPP-3-iTBX study).
- Source :
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BMC geriatrics [BMC Geriatr] 2019 Jan 25; Vol. 19 (1), pp. 24. Date of Electronic Publication: 2019 Jan 25. - Publication Year :
- 2019
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Abstract
- Background: Medication safety is an important health issue for nursing home residents (NHR). They usually experience polypharmacy and often take potentially inappropriate medications (PIM) and antipsychotics. This, coupled with a frail health state, makes NHR particularly vulnerable to adverse drug events (ADE). The value of systematic medication reviews and interprofessional co-operation for improving medication quality in NHR has been recognized. Yet the evidence of a positive effect on NHR' health and wellbeing is inconclusive at this stage. This study investigates the effects of pharmacists' medication reviews linked with measures to strengthen interprofessional co-operation on NHR' medication quality, health status and health care use.<br />Methods: Pragmatic cluster randomised controlled trial in nursing homes in four regions of Germany. A total of 760 NHR will be recruited. Inclusion: NHR aged 65 years and over with an estimated life expectancy of at least six months. Intervention with four elements: i) introduction of a pharmacist's medication review combined with a communication pathway to the prescribing general practitioners (GPs) and nursing home staff, ii) facilitation of change in the interprofessional cooperation, iii) educational training and iv) a "toolbox" to facilitate implementation in daily practice.<br />Analysis: primary outcome - proportion of residents receiving PIM and ≥ 2 antipsychotics at six months follow-up. Secondary outcomes - cognitive function, falls, quality of life, medical emergency contacts, hospital admissions, and health care costs.<br />Discussion: The trial assesses the effects of a structured interprofessional medication management for NHR in Germany. It follows the participatory action research approach and closely involves the three professional groups (nursing staff, GPs, pharmacists) engaged in the medication management. A handbook based on the experiences of the trial in nursing homes will be produced for a rollout into routine practice in Germany.<br />Trial Registration: Registered in the German register of clinical studies (DRKS, study ID DRKS00013588 , primary register) and in the WHO International Clinical Trials Registry Platform (secondary register), both on 25th January 2018.
- Subjects :
- Accidental Falls prevention & control
Aged
Aged, 80 and over
Cluster Analysis
Drug-Related Side Effects and Adverse Reactions epidemiology
Drug-Related Side Effects and Adverse Reactions prevention & control
Female
Follow-Up Studies
General Practitioners standards
General Practitioners trends
Germany epidemiology
Humans
Inappropriate Prescribing trends
Male
Nursing Homes trends
Patient Care Team trends
Pharmacists standards
Pharmacists trends
Potentially Inappropriate Medication List trends
Quality of Life psychology
Inappropriate Prescribing prevention & control
Nursing Homes standards
Patient Care Team standards
Polypharmacy
Potentially Inappropriate Medication List standards
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2318
- Volume :
- 19
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- BMC geriatrics
- Publication Type :
- Academic Journal
- Accession number :
- 30683060
- Full Text :
- https://doi.org/10.1186/s12877-019-1027-0